Our collaborative paper describing a zinc metallochaperone with Eric Skaar’s group appears in Cell!

Our collaborative paper entitled “Zn regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis” appears in Cell today! ┬áThis massive collaborative paper documents the very first zinc metallochaperone, ZNG1, which metalates methionine aminopeptidase-1 under conditions of cellular zinc deficiency. ┬áCongratulations to Katie and Matthew who contributed stunning NMR and key biochemical data that collectively define the structural and thermodynamic underpinnings of Zn chaperone activity!