June 9, 2022

Read Tom O’Halloran’s preview published in Cell today of our work on the zinc metallochaperone ZNG1 published in the same issue of Cell, as well as a companion paper published in Cell Reports on the yeast homolog, Zng1p.

May 25, 2022

This podcast was created by Indiana University!

May 20, 2022

From @IUImpact and the IU Office of the Vice President for Research. Read the story here!

May 20, 2022

Read the story here!

May 17, 2022

Yifan’s paper entitled “SifR is an Rrf2-family quinone sensor associated with catechol iron uptake in Streptococcus pneumoniae D39″ is accepted for publication as an Editor’s Pick in the Journal of Biological Chemistry and is now published.  Congratulations to Katie as well, and to Profs. Julia Martin (Idaho State University) and Malcolm Winkler (IU) who got Yifan started on this very cool story!

May 17, 2022

Our collaborative paper entitled “Zn regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis” appears in Cell today!  This massive collaborative paper documents the very first zinc metallochaperone, ZNG1, which metalates methionine aminopeptidase-1 under conditions of cellular zinc deficiency.  Congratulations to Katie and Matthew who contributed stunning NMR and key biochemical data that collectively define the structural and thermodynamic underpinnings of Zn chaperone activity!

May 13, 2022

Matthew’s comprehensive chapter entitled “Transition metal homeostasis: Metalloprotein paralogs in the bacterial adaptive response to zinc restriction” has been submitted for publication to the editors for review at Comprehensive Inorganic Chemistry III.  Stay tuned!  Congratulations Matthew!!


May 3, 2022

Joe’s protocol paper that outlines a “how-to” guide to cysteine thiol profiling entitled “Protocol for using organic persulfides to measure the chemical reactivity of persulfide sensors” was accepted for publication in STAR Protocols.  Congratulations to both Joe and Dr. Daiana Capdevila for this nice contribution to the literature.

May 2, 2022

Yifan and Katie’s manuscript entitled “Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine” has been posted as a preprint on BioRxiv and is now under peer review.  Fingers crossed!  Congratulations also to co-authors Dr. Giovanni Gonzalez-Gutierrez and Katherine Legg!

March 23, 2022

Joey was named a winner of the Kindig fellowship which will provide stipend support in his third academic year here.  Joey’s project is focused on structural and dynamical studies of an usual COG0523 enzyme in Acinetobacter baumannii.  Congratulations Joey!!