November 27, 2024
This manuscript describes the function of a new COG0523 protein in Acinetobacter baumannii that we designate MigC. Congratulations to graduate students Jeanette Crithlow in Eric Skaar’s group and Joey Rocchio in my group for bringing this to fruition!! More soon!!!
November 19, 2024
This work, co-authored by Drs. Katie Edmonds and Karla Diaz-Rodriguez, describes the first purification of heterotetrameric EgtU, which transports the low-molecular weight thiol, ergothioneine, into bacterial cells. This paper can be accessed here. Congratulations to Katie and Karla!!
November 6, 2024
This review (…my little sabbatical project!!) provides an up-to-date account of many aspects of bacterial metallostasis and can be accessed via this doi link. This paper should be online any day now! Thanks to Joey Rocchio and Dr. Katie Edmonds in my group and Dr. Daiana Capdevila in Argentina for their significant contributions to this work!!
November 5, 2024
Katie will oversee training and usage of an existing 600 MHz solutions instrument and a new Bruker Ascend 800 MHz hybrid solutions/ssNMR instrument now fully installed and operational in the METACyt Biomolecular NMR Laboratory in the basement of Simon Hall. Congratulations Katie!!
September 24, 2024
Katherine Legg performed low molecular weight thiol profiling of these sputum samples as part of a larger work originating with Michelle Reinier’s group at the University of Washington. This manuscript describes the genetic requirements and nutrient availability for the growth of Staphylococcus aureus in cystic fibrosis sputum. This preprint can be accessed here and is currently under peer review. Congratulations Katherine!!
September 22, 2024
This paper describes collaborative work on an emerging topic that describes a new intersection of sRNAs and metal homeostasis. The work originated with the De Lay group at University of Texas Health Science Center Houston, and involved Malcolm Winkler’s group here at IU and my group. Max Osterberg and QCB trainee Abigail Garrett in the Winkler group are co-authors on this paper. Congratulations to Max and to Abigail!! This is peer-reviewed paper #200 by Prof Giedroc, a significant milestone!
August 1, 2024
Karla received her graduate training in her native Peru, and comes to us following two years of postdoctoral experience in the Arguello group at WPI. Karla will work on the ergothioneine transporter and RSS projects in the group. Welcome Karla!!
April 23, 2024
Dr Britta Rued, a Microbiology Ph.D. student co-advised by Profs. Winkler and Giedroc, will start her independent faculty position in the Department of Veterinary Microbiology and Preventive Medicine in the College of Veterinary Medicine at Iowa State University in August 2024. Britta is a former QCB trainee at IU and is a K99 awardee with Prof. Michael Federle’s group at UIC.
April 23, 2024
Max Osterberg has been awarded a $650 Paget Travel Grant by the Department of Chemistry to attend the 9th International Symposium on Metallomics to be held in London in June 2024. Congratulations Max!
March 5, 2024
Max’s paper describing the Zn(II) coordination chemistry, G-nucleotide-induced folding and extensive hydrogen-deuterium exchange-mass spectrometry (HDX-MS) of the bacterial COG0523 enzyme, Acinetobacter baumannii ZigA, is accepted today in Biophysical Journal. Happy birthday Max! Congratulations also to our collaborators Tim Stemmler (Wayne State) and Daniel Deredge (University of Maryland Baltimore).