December 8, 2022

Yifan’s paper describing the discovery and structural characterization of a highly specific transporter for the low molecular weight thiol/thione, ergothioneine, in the respiratory pathogen, Streptococcus pneumoniae, appears online today in Nature Communications!  Congratulations to Yifan, Katie and Katherine!!

December 4, 2022

Emma McRae, a new Chemistry graduate student in chemical biology, joins the group. Emma completed her undergraduate degree in chemical biology at UC Berkeley, where she carried out undergraduate research with Michael Marletta. Welcome, Emma!

November 23, 2022

Dr. Yifan Zhang will begin a postdoctoral appointment on December 1 in Prof. Taosheng Chen’s group at St. Jude Children’s Research Hospital in the Department of Chemical Biology & Therapeutics in the Comprehensive Cancer Center there.  Good luck Yifan!

November 8, 2022

Matthew’s paper connecting transition metal starvation to flux through the queuosine-tRNA biosynthetic pathway in a bacterial pathogen is accepted for publication in the Proceedings of the National Academy of Sciences USA!  This paper describes fundamental insights on QueD2, a 6-CPH4-synthase and “low-zinc paralog” that becomes cell-abundant under conditions of calprotectin-mediated Zn/Fe restriction in Acinetobacter baumannii.  Congratulations Matthew!

November 1, 2022

Matthew has left the Giedroc laboratory for postdoctoral appointment in John Turchi’s laboratory at the IU School of Medicine.  Good luck Matthew!

September 30, 2022

Joey Rocchio, a third-year Chemistry student and Kindig Fellowship recipient, has passed his candidacy examinations with flying colors!  Welcome to Ph.D. candidacy!

August 30, 2022

Matthew Jordan successfully defends his Ph.D. work in a beautifully presented public seminar and an outstanding defense of the project.  Congratulations Dr. Jordan!

August 25, 2022

Our paper that describes aspects of the structural, proteomic and metabolic response to hydrogen sulfide stress in the gut bacterium Enterococcus faecalis appears online (open access) in Antioxidants.  Congratulations to Brenna and collaborators José Brito and Federico Issoglio on the structure and dynamical analysis of Ef coenzyme A persulfide reductase!  The “swinging pantothenate arm” re-appears!

August 4, 2022

Check out Prof. Wolfgang Maret’s News and Views piece in Nature, reviewing the discovery and characterization of ZNG1 that we published with the Skaar group in Cell!

July 13, 2022

Matthew’s chapter summarizes all that is known about low-zinc parologs as a key part of the bacterial adaptive response to Zn starvation is accepted for publication in Comprehensive Inorganic Chemistry III.  Congratulations Matthew!